Tag: breast cancer

Palbociclib and hormonal therapy has proven progression-free survival benefit

In hormone-positive metastatic breast cancer, combination therapy with palbociclib and hormonal therapy has proven progression-free survival benefit Palbociclib is an oral drug that inhibits cell cycle growth by blocking cells from initiating initial switch to the growth cycle of cells though CDK4 (Cyclin D-Dependent Kinase) and CDK 6 inhibition. This drug has been found to… Read more »


Small benefit to extended hormonal treatment of breast cancer

This summer, we finally received trial results about an important clinical question: does extended aromatase inhibitor (“hormonal”) treatment of breast cancer from 5 years to 10 years affect long-term outcomes in breast cancer survivors? Post-menopausal patients with estrogen or protesterone positive breast cancer were randomized to receive either 5 years or 10 years of aromatase… Read more »